??? ??????? ??????? ???? ???? ?? ????? ???? ??? ?????? ??? ????? ??? ????? ???? ??? ????.?????? ???????? ?? ???? ??? ?? ?? ?????? ??????? ??? ??? ???? ???????? ??????? ???? ?? ????? ??????. ??? ??????? ?????? ?? ??? ?? ????? ???????. - ???? ??????Secondary efficacy endpoints include things like SPID24, complete use (mg) of rescue (supplemental) an